Image | Item No. | Description |
| 76145-1 (Inv) | Eternals’ Aerial Assault 125 Parts, 2 Minifigures, 2021 Catalog: Sets: Super Heroes: Eternals |
| 76154-1 (Inv) | Deviant Ambush! 185 Parts, 3 Minifigures, 2021 Catalog: Sets: Super Heroes: Eternals |
| 76156-1 (Inv) | Rise of the Domo 1016 Parts, 6 Minifigures, 2021 Catalog: Sets: Super Heroes: Eternals |
| 76168-1 (Inv) | Captain America Mech Armor 117 Parts, 1 Minifigure, 2021 Catalog: Sets: Super Heroes: Avengers |
| 76171-1 (Inv) | Miles Morales Mech Armor 121 Parts, 1 Minifigure, 2021 Catalog: Sets: Super Heroes: Spider-Man |
| 76175-1 (Inv) | Attack on the Spider Lair 437 Parts, 6 Minifigures, 2021 Catalog: Sets: Super Heroes: Spider-Man |
| 76184-1 (Inv) | Spider-Man vs. Mysterio's Drone Attack 62 Parts, 3 Minifigures, 2021 Catalog: Sets: Super Heroes: Spider-Man No Way Home |
| 76185-1 (Inv) | Spider-Man at the Sanctum Workshop 339 Parts, 4 Minifigures, 2021 Catalog: Sets: Super Heroes: Spider-Man No Way Home |
| 76186-1 (Inv) | Black Panther Dragon Flyer 191 Parts, 3 Minifigures, 2021 Catalog: Sets: Super Heroes: The Infinity Saga |
| 76190-1 (Inv) | Iron Man: Iron Monger Mayhem 468 Parts, 3 Minifigures, 2021 Catalog: Sets: Super Heroes: The Infinity Saga |
| 76194-1 (Inv) | Tony Stark’s Sakaarian Iron Man 355 Parts, 3 Minifigures, 2021 Catalog: Sets: Super Heroes: What If...? |
| 76195-1 (Inv) | Spider-Man's Drone Duel 188 Parts, 2 Minifigures, 2021 Catalog: Sets: Super Heroes: Spider-Man No Way Home |